Local bus stop very frequently and travel with them in on way to learn you way around the city. Fell free to ask the drivers or conductors for your desired location usually they are very polite.

For major detinationes, buses leave every 30-45 minuts in sevaral bus station.

from mercado Roberto Humbres:Departures for Granada,Masaya,Rivas(to reach San jorge for ferries to Isla de Ometepe) and Tipitapa.Expresos and directors depart horly from the left outgoing side of the bus plaza.

From mercado Israel Lewites: departures for Chinandega, Jinotepe, Leon and Pochomil. Expresosdepart frequently for Chinandega and Leon.

From mercado Mayoreo: departure for Boaco, Esteli, Jugigalpa, Matagalpa, Ocotal, Rama, Siuna and Somoto. Expresos depart frequently for Esteli and Matagalpa.

From U.C.A. (Central America university) depart expresos for Granada, Masaya, Jinotepe and Carazo. Espresos depart every 20 minutes.